The Eternal derby, which is also known as the ‘Derby of Southeast Europe,’ has resulted in tense confrontations both on the pitch and off it.
And FootballFanCast ranked the rivalry at the top of its 20 biggest rivalries in football history.
The publication said that the ‘passion and exhilaration the fans inherit comes from the success on the pitch with the result.’
And FootballFanCast added that passion and exhilaration could also lead to supporters clashing off the pitch, with riot police having a ‘huge job on their hands when this comes around.’
The iconic Old Firm derby between Celtic and Rangers ranked third, while Barcelona and Real Madrid’s legendary El Clasico rivalry also made the top 10.
Posted below are the 20 biggest rivalries in world football, according to FootballFanCast.
20. Manchester City vs Manchester United (Manchester derby)
19. Arsenal vs Tottenham Hotspur (North London derby)
18. AC Milan vs Inter Milan (Derby della Madonnina)
17. Liverpool vs Everton (Merseyside derby)
16. Bayern Munich vs Borussia Dortmund (Der Klassiker)
15. Sunderland vs Newcastle United (Tyne-Wear derby)
14. Aston Villa vs Birmingham City (Second City derby)
13. Liverpool vs Manchester United (North West derby)
12. West Ham vs Millwall (London derby)
11. Ajax vs Feyenoord (De Klassieker)
10. Olympiakos vs Panathinaikos (‘Derby of Eternal Enemies’)
9. Barcelona vs Real Madrid (El Clasico)
8. Galatasaray vs Fenerbahce (Intercontinental derby)
7. Penarol vs Nacional (Uruguayan Clasico)
6. Lazio vs Roma (Derby della Capitale)
5. Flamengo vs Fluminense (Fla-Flu derby)
4. Al Ahly vs Zamalek (Cairo derby)
3. Celtic vs Rangers (Old Firm derby)
2. Boca Juniors vs River Plate (Superclasico)
1. Red Star Belgrade vs Partizan Belgrade (Eternal derby)